| 论文题目: | Diketopiperazines from the Cordyceps-colonizing fungus Epicoccum nigrum. |
|---|---|
| 作者: | Huijuan Guo, Bingda Sun, Hao Gao, Xulin Chen, Shuchun Liu, Xinsheng Yao, Xingzhong Liu and Yongsheng Che* |
| 联系作者: | 车永胜 |
| 刊物名称: | Journal of Natural Products |
| 期: | 12 |
| 卷: | 72 |
| 页: | 2115-2119 |
| 年份: | 2010 |
| 影响因子: | 3.159 |
| 论文下载: | 下载地址 |
| 摘要: | New diketopiperazines, epicoccins E−H (1−4) and diphenylalazines A (5) and B (6), have been isolated from the solid-substrate fermentation culture of the Cordyceps-colonizing fungus Epicoccum nigrum. The structures of 1−6 were determined primarily by NMR experiments, and the structure of 1 was confirmed by X-ray crystallography. The absolute configurations of 3 and 5 were assigned using the modified Mosher (3) and Marfey’s (5) methods, respectively. Compounds 3−5 showed inhibitory effects on HIV-1 replication in C8166 cells. |
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