| 论文题目: | Bacillus sp. strain P38: An efficient producer of l-lactate from cellulosic hydrolysate, with high tolerance for 2-furfural |
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| 作者: | Peng Lili, Wang Limin, Che Chengchuan, Yang Ge, Yu Bo*, Ma Yanhe |
| 联系作者: | Yu Bo* |
| 刊物名称: | Bioresource Technology |
| 期: | |
| 卷: | |
| 页: | 169-176 |
| 年份: | 2013 |
| 影响因子: | 5.172 |
| 论文下载: | 下载地址 |
| 摘要: | In this study, efficient polymer-grade l-lactic acid production was achieved with the strain Bacillus sp. P38 by using cellulosic hydrolysate as the sole carbon source. In fed-batch fermentation, 180gL-1l-lactic acid was obtained with a volumetric productivity of 2.4gL-1h-1 and a yield of 0.96gg-1 total reducing sugars. No d-isomer of lactic acid was detected in the broth. Strain P38 tolerated up to 10gL-1 2-furfural, and lactate production was sharply inhibited only when the 2-furfural concentration was higher than 6gL-1. Moreover, strain P38 also tolerated high concentrations (>6gL-1) of other fermentation inhibitors in cellulosic hydrolysate, such as vanillin and acetic acid, although it was slightly sensitive to formic acid. The efficient l-lactic acid production, combined with high inhibitor tolerance and efficient pentose utilization, indicate that Bacillus sp. P38 is a promising producer of polymer-grade l-lactic acid from cellulosic biomass. |
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