| 论文题目: | Efficient production of polymer-grade L-lactate by an alkaliphilic Exiguobacterium sp strain under nonsterile open fermentation conditions |
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| 作者: | Jiang Xu, Xue Yanfen, Wang Aiyan, Wang Limin, Zhang Guimin, Zeng Qingtao, Yu Bo*, Ma Yanhe |
| 联系作者: | Yu Bo* |
| 刊物名称: | Bioresource Technology |
| 期: | |
| 卷: | 143 |
| 页: | 665-668 |
| 年份: | 2013 |
| 影响因子: | 5.172 |
| 论文下载: | 下载地址 |
| 摘要: | In this study, a newly isolated alkaliphile Exiguobacterium sp. strain 8-11-1 was used to produce optically pure L-lactate. With an initial glucose concentration of 80 g/L, a high overall L-lactic acid productivity of 8.15 g/L/h was achieved using NaOH as a neutralizing agent. The fed-batch fermentations were carried out under both sterile and nonsterile conditions. Under the nonsterile condition, 125 g/L L-lactic acid was obtained with a high percent yield and average productivity of 98.33% and 3.79 g/L/h, respectively. These values were consistent with the results from sterile condition. No D-isomers of lactic acid were detected, resulting in an optical purity of 100% in both conditions. The high levels of optically pure L-lactic acid produced by Exiguobacterium sp. 8-11-1, combined with the ease of handling and low costs associated with the open fermentation strategy, provide a novel and potentially important approach for L-lactic acid production in the future. (C) 2013 Elsevier Ltd. All rights reserved. |
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